Auditory system of fruit flies

• The fruit fly is an invaluable model for auditory research.
• Fruit flies use courtship songs in their mating behavior.
• Systematic mapping of auditory neurons reveals the organization of auditory pathways.
• The auditory systems of mammals and fruit flies are strikingly similar.

The fruit fly, Drosophila melanogaster, is an invaluable model for auditory research. Advantages of using the fruit fly include its stereotyped behavior in response to a particular sound, and the availability of molecular-genetic tools to manipulate gene expression and cellular activity. Although the receiver type in fruit flies differs from that in mammals, the auditory systems of mammals and fruit flies are strikingly similar with regard to the level of development, transduction mechanism, mechanical amplification, and central projections. These similarities strongly support the use of the fruit fly to study the general principles of acoustic information processing. In this review, we introduce acoustic communication and discuss recent advances in our understanding on hearing in fruit flies.This article is part of a Special Issue entitled .