On existence of reporter strands in DNA-based graph structures

Through self-assembly of branched junction molecules many different DNA structures (graphs) can be assembled. We show that every multigraph can be assembled by DNA such that there is a single strand that traces each edge in the graph at least once. This strand corresponds to a boundary component of a two-dimensional orientable surface that has the given graph as a deformation retract. This boundary component traverses every edge at least once, and it defines a circular path in the graph that “preserves the graph structure” and traverses each edge.