IDD-based model validation of biochemical networks

This paper presents efficient techniques for the qualitative and quantitative analysis of biochemical networks, which are modeled by means of qualitative and stochastic Petri nets, respectively. The analysis includes standard Petri net properties as well as model checking of the Computation Tree Logic and the Continuous Stochastic Logic. Efficiency is achieved by using Interval decision diagrams to alleviate the well-known problem of state space explosion, and by applying operations exploiting the Petri structure and the principle of locality. All presented techniques are implemented in our tool IDD-MC which is available on our website.