کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4392454 1618171 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glycolipoprotein extract of Eisenia foetida (G-90): A source of biological active molecules
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش خاک شناسی
پیش نمایش صفحه اول مقاله
Glycolipoprotein extract of Eisenia foetida (G-90): A source of biological active molecules
چکیده انگلیسی

The G-90 is a macromolecular mixture with glycolipoprotein characteristics obtained from tissue homogenate of the earthworm Eisenia foetida. This macromolecular mixture exhibits numerous biological activities such as mitogenicity, anticoagulation, fibrinolysis, bacteriostasis and antioxidation in vitro and in vivo conditions. It is neither mutagenic nor cancerogenic. In our investigation G-90 did not contain the growth factors (FGF and EGF), but it stimulated their synthesis in cell cultures, which caused increased cell proliferation. It is likely that some pleiotropic activity of G-90 could be associated with the insulin-like proteins, tyrosine like serine peptidases and the immunoglobulin-like molecules. Some factors in G-90 recognised sera of patients with tumors, as well as those suffering from cardiopathies. Accordingly, G-90 is a valuable mixture of biologically active macromolecules, which could be very useful in human and veterinary medicine.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Soil Biology - Volume 43, Supplement 1, November 2007, Pages S104–S109
نویسندگان
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