کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
444061 | 692866 | 2014 | 16 صفحه PDF | دانلود رایگان |
• In our knowledge, no method for tractography shares information between particles.
• We propose a probabilistic tractography method based on the flocking concept.
• Improvements by using a collective information term on the particle motion are shown.
• The gravitational force between particles gives that collective information.
• Our proposal obtains the best performance on the Fiber Cup data.
We propose a new method to estimate axonal fiber pathways from Multiple Intra-Voxel Diffusion Orientations. Our method uses the multiple local orientation information for leading stochastic walks of particles. These stochastic particles are modeled with mass and thus they are subject to gravitational and inertial forces. As result, we obtain smooth, filtered and compact trajectory bundles. This gravitational interaction can be seen as a flocking behavior among particles that promotes better and robust axon fiber estimations because they use collective information to move. However, the stochastic walks may generate paths with low support (outliers), generally associated to incorrect brain connections. In order to eliminate the outlier pathways, we propose a filtering procedure based on principal component analysis and spectral clustering. The performance of the proposal is evaluated on Multiple Intra-Voxel Diffusion Orientations from two realistic numeric diffusion phantoms and a physical diffusion phantom. Additionally, we qualitatively demonstrate the performance on in vivo human brain data.
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Journal: Medical Image Analysis - Volume 18, Issue 3, April 2014, Pages 515–530