کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
444068 692866 2014 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Automatic segmentation of intra-cochlear anatomy in post-implantation CT of unilateral cochlear implant recipients
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر گرافیک کامپیوتری و طراحی به کمک کامپیوتر
پیش نمایش صفحه اول مقاله
Automatic segmentation of intra-cochlear anatomy in post-implantation CT of unilateral cochlear implant recipients
چکیده انگلیسی


• We established that intra-cochlear anatomy and the labyrinth are symmetric.
• We built a statistical shape model of the labyrinth.
• We automatically segmented the labyrinth in the normal ear.
• We automatically segmented the intra-cochlear anatomy in the implanted ear by exploiting the information of symmetry.
• We report that the method accurately segments the intra-cochlear anatomy in the implanted ear.

A cochlear implant (CI) is a neural prosthetic device that restores hearing by directly stimulating the auditory nerve using an electrode array that is implanted in the cochlea. In CI surgery, the surgeon accesses the cochlea and makes an opening where he/she inserts the electrode array blind to internal structures of the cochlea. Because of this, the final position of the electrode array relative to intra-cochlear anatomy is generally unknown. We have recently developed an approach for determining electrode array position relative to intra-cochlear anatomy using a pre- and a post-implantation CT. The approach is to segment the intra-cochlear anatomy in the pre-implantation CT, localize the electrodes in the post-implantation CT, and register the two CTs to determine relative electrode array position information. Currently, we are using this approach to develop a CI programming technique that uses patient-specific spatial information to create patient-customized sound processing strategies. However, this technique cannot be used for many CI users because it requires a pre-implantation CT that is not always acquired prior to implantation. In this study, we propose a method for automatic segmentation of intra-cochlear anatomy in post-implantation CT of unilateral recipients, thus eliminating the need for pre-implantation CTs in this population. The method is to segment the intra-cochlear anatomy in the implanted ear using information extracted from the normal contralateral ear and to exploit the intra-subject symmetry in cochlear anatomy across ears. To validate our method, we performed experiments on 30 ears for which both a pre- and a post-implantation CT are available. The mean and the maximum segmentation errors are 0.224 and 0.734 mm, respectively. These results indicate that our automatic segmentation method is accurate enough for developing patient-customized CI sound processing strategies for unilateral CI recipients using a post-implantation CT alone.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Image Analysis - Volume 18, Issue 3, April 2014, Pages 605–615
نویسندگان
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