کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4493375 1623655 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Histopathology biomarker responses in Asian sea bass, Lates calcarifer (Bloch) exposed to copper
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Histopathology biomarker responses in Asian sea bass, Lates calcarifer (Bloch) exposed to copper
چکیده انگلیسی

Copper is a trace element necessary for the normal growth and metabolism of living organisms. If exceeds its limit it becomes pollutant and causes pathological effects. Asian sea bass (Lates calcarifer) was exposed to sublethal concentrations of copper for 28 days and histopathological alterations were noticed in the gill, liver, muscle and intestine. Epithelial necrosis, hypertrophy, rupture of gill epithelium and haemorrhage at primary lamellae were observed after 7 days of exposure. Lifting of epithelium, oedema and fusion of adjacent secondary lamellae were conspicuous at 28 days of exposure. The experimental liver tissue showed reduction in the size of hepatocytes, vacuolisation, and hypertrophy. The intestine displayed fused microvilli, sloughing of mucus membrane and swollen cells. Muscle bundles with severe oedema and their thickening and separation were more pronounced in sublethal treatment of copper in the muscle. Several histopathological changes observed in various fish organs would serve a useful purpose in evaluating the toxic effects of copper. The present study clearly demonstrated that all the treated body organs exhibited significant damage with response; amongst the body organs the liver is an important target organ for copper toxicity in L. calcarifer and this species could be possibly used as a model organism for toxicity studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Basic & Applied Zoology - Volume 77, October 2016, Pages 21–30
نویسندگان
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