کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4497135 1318918 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genome analysis with the conditional multinomial distribution profile
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Genome analysis with the conditional multinomial distribution profile
چکیده انگلیسی

The focus of the research is on the analysis of genome sequences. Based on the inter-nucleotide distance sequence, we propose the conditional multinomial distribution profile for the complete genomic sequence. These profiles can be used to define a very simple, computationally efficient, alignment-free, distance measure that reflects the evolutionary relationships between genomic sequences. We use this distance measure to classify chromosomes according to species of origin, to build the phylogenetic tree of 24 complete genome sequences of coronaviruses. Our results demonstrate the new method is powerful and efficient.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 271, Issue 1, 21 February 2011, Pages 44–50
نویسندگان
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