کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4497459 1318935 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dynamical behavior of a hepatitis B virus transmission model with vaccination
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Dynamical behavior of a hepatitis B virus transmission model with vaccination
چکیده انگلیسی

Hepatitis B virus (HBV) infection is a globally health problem. In 2005, the WHO Western Pacific Regional Office set a goal of reducing chronic HBV infection rate to less than 2% among children five years of age by 2012, as an interim milestone towards the final goal of less than 1%. Many countries made some plans (such as free HBV vaccination program for all neonates in China now) to control the transmission HBV. We develop a model to explore the impact of vaccination and other controlling measures of HBV infection. The model has simple dynamical behavior which has a globally asymptotically stable disease-free equilibrium when the basic reproduction number R0≤1R0≤1, and a globally asymptotically stable endemic equilibrium when R0>1R0>1. Numerical simulation results show that the vaccination is a very effective measure to control the infection and they also give some useful comments on controlling the transmission of HBV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 265, Issue 4, 21 August 2010, Pages 572–578
نویسندگان
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