کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4498788 1318999 2007 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Initiation of cytoskeletal asymmetry for cell polarization and movement
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Initiation of cytoskeletal asymmetry for cell polarization and movement
چکیده انگلیسی

A variety of mathematical models for the actin driven motility of eucaryotic cells have been discussed over the last decades. However, most of them do model polarized cells which are already in motion or at least have established lamellipods. Here we investigate the stimulus induced transition from a symmetric resting state of a cell to a polarized one. Our goal is to find a minimal scenario for this rearrangement of the cytoskeleton and to figure out which of the manifold proteins and processes associated with actin dynamics are essential for the initiation of movement.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 249, Issue 2, 21 November 2007, Pages 278–288
نویسندگان
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