کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4499375 1319028 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A stochastic model in tumor growth
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
A stochastic model in tumor growth
چکیده انگلیسی

A stochastic model of solid tumor growth based on deterministic Gompertz law is presented. Tumor cells evolution is described by a one-dimensional diffusion process limited by two absorbing boundaries representing healing threshold and patient death (carrying capacity), respectively. Via a numerical approach the first exit time problem is analysed for the process inside the region restricted by the boundaries. The proposed model is also implemented to simulate the effects of a time-dependent therapy. Finally, some numerical results are obtained for the specific case of a parathyroid tumor.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 242, Issue 2, 21 September 2006, Pages 329–336
نویسندگان
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