کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4499542 | 1623929 | 2006 | 10 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Alignments of mitochondrial genome arrangements: Applications to metazoan phylogeny Alignments of mitochondrial genome arrangements: Applications to metazoan phylogeny](/preview/png/4499542.png)
Mitochondrial genomes provide a valuable dataset for phylogenetic studies, in particular of metazoan phylogeny because of the extensive taxon sample that is available. Beyond the traditional sequence-based analysis it is possible to extract phylogenetic information from the gene order. Here we present a novel approach utilizing these data based on cyclic list alignments of the gene orders. A progressive alignment approach is used to combine pairwise list alignments into a multiple alignment of gene orders. Parsimony methods are used to reconstruct phylogenetic trees, ancestral gene orders, and consensus patterns in a straightforward approach. We apply this method to study the phylogeny of protostomes based exclusively on mitochondrial genome arrangements. We, furthermore, demonstrate that our approach is also applicable to the much larger genomes of chloroplasts.
Journal: Journal of Theoretical Biology - Volume 240, Issue 4, 21 June 2006, Pages 511–520