کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4503118 1624176 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
On modelling the immune system as a complex system
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات مدل‌سازی و شبیه سازی
پیش نمایش صفحه اول مقاله
On modelling the immune system as a complex system
چکیده انگلیسی
We argued that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It has the property that every antigen (e.g. virus or bacteria) is typically attacked by more than one effector. This stabilizes the equilibrium state. Modelling complex systems is discussed. Cellular automata (CA)-type models are successful, but there are much less analytic results about CA than about other less successful models e.g. partial differential equations (PDE). A compromise is proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theory in Biosciences - Volume 124, Issues 3–4, 1 March 2006, Pages 413-418
نویسندگان
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