کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4503118 | 1624176 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
On modelling the immune system as a complex system
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موضوعات مرتبط
مهندسی و علوم پایه
ریاضیات
مدلسازی و شبیه سازی
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چکیده انگلیسی
We argued that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It has the property that every antigen (e.g. virus or bacteria) is typically attacked by more than one effector. This stabilizes the equilibrium state. Modelling complex systems is discussed. Cellular automata (CA)-type models are successful, but there are much less analytic results about CA than about other less successful models e.g. partial differential equations (PDE). A compromise is proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theory in Biosciences - Volume 124, Issues 3â4, 1 March 2006, Pages 413-418
Journal: Theory in Biosciences - Volume 124, Issues 3â4, 1 March 2006, Pages 413-418
نویسندگان
E. Ahmed, A.H. Hashish,