کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4531303 | 1324768 | 2006 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Coplanar and non-coplanar congener-specificity of PCB bioaccumulation and immunotoxicity in sea stars Coplanar and non-coplanar congener-specificity of PCB bioaccumulation and immunotoxicity in sea stars](/preview/png/4531303.png)
The sea star Asterias rubens (L.), a representative species of the North Sea benthic environment, was exposed to a mixture of 10 selected PCB congeners (3 coplanar or c-PCBs, and 7 non-coplanar) via experimentally contaminated sediments. Both the degree of bioaccumulation and subsequent immunotoxic effects of these PCBs were determined. A strong congener-specificity for both bioaccumulation and immunotoxicity was found as well as a probable induction of a congener-specific detoxification mechanism resulting in the dramatic decrease in body levels of the three coplanar congeners tested (PCBs 77, 126 and 169). Moreover, a correlation was found between the bioaccumulation of c-PCBs and their immunotoxic effects. These findings suggest that coplanar congeners should be included in the list of congeners recommended to be analyzed for biological impact-oriented marine monitoring programmes.
Journal: Aquatic Toxicology - Volume 79, Issue 2, 23 August 2006, Pages 105–113