کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4602938 1631172 2008 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Balancing control and simplicity: A variable aggregation method in intensity modulated radiation therapy planning
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات اعداد جبر و تئوری
پیش نمایش صفحه اول مقاله
Balancing control and simplicity: A variable aggregation method in intensity modulated radiation therapy planning
چکیده انگلیسی

It is commonly believed that not all degrees of freedom are needed to produce good solutions for the treatment planning problem in intensity modulated radiation therapy (IMRT). However, typical methods to exploit this fact either increase the complexity of the optimization problem or are heuristic in nature. In this work we introduce a technique based on adaptively refining variable clusters to successively attain better treatment plans. The approach creates approximate solutions based on smaller models that may come arbitrarily close to the optimal solution. Although the method is illustrated using a specific treatment planning model, the components constituting the variable clustering and the adaptive refinement are independent of the particular optimization problem.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Linear Algebra and its Applications - Volume 428, Issues 5–6, 1 March 2008, Pages 1388-1405