کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4752496 1416159 2016 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewMultifunctional gold-based nanocomposites for theranostics
ترجمه فارسی عنوان
بررسی نانو کامپوزیت های مبتنی بر طلا چند منظوره برای تانونستیک
کلمات کلیدی
نانوذرات طلا، ترانوسستیک، نانوکامپوزیت ها، چند منظوره سازی،
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی

Although Au-particle potential in nanobiotechnology has been recognized for the last 15 years, new insights into the unique properties of multifunctional nanostructures have just recently started to emerge. Multifunctional gold-based nanocomposites combine multiple modalities to improve the efficacy of the therapeutic and diagnostic treatment of cancer and other socially significant diseases. This review is focused on multifunctional gold-based theranostic nanocomposites, which can be fabricated by three main routes. The first route is to create composite (or hybrid) nanoparticles, whose components enable diagnostic and therapeutic functions. The second route is based on smart bioconjugation techniques to functionalize gold nanoparticles with a set of different molecules, enabling them to perform targeting, diagnostic, and therapeutic functions in a single treatment procedure. Finally, the third route for multifunctionalized composite nanoparticles is a combination of the first two and involves additional functionalization of hybrid nanoparticles with several molecules possessing different theranostic modalities. This last class of multifunctionalized composites also includes fluorescent atomic clusters with multiple functionalities.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 108, November 2016, Pages 13-34
نویسندگان
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