کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4909536 | 1362624 | 2016 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biological activities of imidazo[2,1-b][1,3,4]thiadiazole derivatives: A review
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
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چکیده انگلیسی
Imidazo[2,1-b][1,3,4]thiadiazole heterocycle was discovered during the 1950s. Since then, many newer derivatives are being developed and evaluated for their biological profiles. The derivatives of imidazo[2,1-b][1,3,4]thiadiazoles are widely explored for their biological potential viz. antimicrobial, antifungal, anticancer, anticonvulsant, analgesic, antiinflammatory, anesthetic, and diuretic. They are also reported as potential enzyme inhibitors of cyclooxygenase, Jun kinase, carbonic anhydrase demonstrating their possible significance in target oriented drug design and discovery. The present review highlights the last six decades of research on biological activities of the imidazo[2,1-b][1,3,4]thiadiazoles.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Saudi Chemical Society - Volume 20, Supplement 1, September 2016, Pages S463-S475
Journal: Journal of Saudi Chemical Society - Volume 20, Supplement 1, September 2016, Pages S463-S475
نویسندگان
Bhoomendra A. Bhongade, Sirajunisa Talath, Ravikiran A. Gadad, Andanappa K. Gadad,