کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4932524 | 1433524 | 2017 | 74 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Neural correlates of durable memories across the adult lifespan: brain activity at encoding and retrieval
ترجمه فارسی عنوان
همبستگی عصبی خاطرات دوام در طول عمر بالغ: فعالیت مغز در رمزگذاری و بازیابی
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
چکیده انگلیسی
Age-related effects on brain activity during encoding and retrieval of episodic memories are well documented. However, research typically tests memory only once, shortly after encoding. Retaining information over extended periods is critical, and there are reasons to expect age-related effects on the neural correlates of durable memories. Here, we tested whether age was associated with the activity elicited by durable memories. One hundred forty-three participants (22-78Â years) underwent an episodic memory experiment where item-context relationships were encoded and tested twice. Participants were scanned during encoding and the first test. Memories retained after 90Â minutes but later forgotten were classified as transient, whereas memories retained after 5Â weeks were classified as durable. Durable memories were associated with greater encoding activity in inferior lateral parietal and posteromedial regions and greater retrieval activity in frontal and insular regions. Older adults exhibited lower posteromedial activity during encoding and higher frontal activity during retrieval, possibly reflecting greater involvement of control processes. This demonstrates that long-lasting memories are supported by specific patterns of cortical activity that are related to age.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Aging - Volume 60, December 2017, Pages 20-33
Journal: Neurobiology of Aging - Volume 60, December 2017, Pages 20-33
نویسندگان
Didac Vidal-Piñeiro, Markus H. Sneve, Andreas B. Storsve, James M. Roe, Kristine B. Walhovd, Anders M. Fjell,