کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5020708 | 1469077 | 2017 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of the mechanical behaviors and bioactivity of tetrapod ZnO whiskers reinforced bioactive glass/gelatin composite scaffolds
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Characterization of the mechanical behaviors and bioactivity of tetrapod ZnO whiskers reinforced bioactive glass/gelatin composite scaffolds Characterization of the mechanical behaviors and bioactivity of tetrapod ZnO whiskers reinforced bioactive glass/gelatin composite scaffolds](/preview/png/5020708.png)
چکیده انگلیسی
The purpose of this study is to construct bone tissue engineering scaffold with high porosity, good mechanical properties, and biological activities. Bioactive glass/gelatin composite scaffolds with different amounts of tetrapod zinc oxide whiskers were produced. The morphology, mechanical properties and in vitro bioactivity of the composite scaffolds were investigated. Results showed that, the composite scaffolds had open pores with a high degree of interconnectivity, and the porosity was higher than 80%. With the amount of ZnO whiskers increased, the mechanical properties of scaffolds increased. However, the reinforcing effect began to decrease when the addition is higher than 2Â wt%, which was resulted by the aggregation of the ZnO whiskers. In vitro test showed that, the composite scaffolds processed good biodegradability, and in vitro apatite-forming ability. The release of zinc ions retarded the growth of the HCA, so the HCA deposited on the scaffolds with ZnO was amorphous and worm-like. Furthermore, the composite scaffolds had good biocompatibility assessed by in vitro cell tests using rMSCs. All results are promising for the application of the composite scaffolds in bone repair.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 68, April 2017, Pages 8-15
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 68, April 2017, Pages 8-15
نویسندگان
Weihuang Guo, Fujian Zhao, Yudong Wang, Jieyin Tang, Xiaofeng Chen,