کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5031913 1471103 2017 29 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biomechanical assessment of the aortic root using novel force transducers
ترجمه فارسی عنوان
ارزیابی بیومکانیک ریشه آئورت با استفاده از مبدل های جدید نیرو
کلمات کلیدی
اندازه گیری نیروی، تکنیک های تعمیر دریچه آئورت، سلولهای آئورت کاربردی،
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
In recent years the use of valve sparing techniques has become more common in selected patients with aortic valve insufficiency. However, limited experimental research has been performed to document the biomechanical effect of these techniques. One experimental platform is to evaluate how the normal physiological aortic root forces are altered or re-established after the surgical intervention. Hence, the aim of this project was to develop new implantable force transducers for a biomechanical description of various aortic root repair techniques. Two novel force transducers were developed. Both transducers were manufactured using rapid prototyping and were instrumented with miniature strain gauges. Before implantation both transducers were calibrated using a dedicated setup, yielding very linear correlation between the applied load and transducer output. The developed force transducers were implanted and tested in an 80 kg porcine model. In the post-cardioplegic heart, the peak annular forces varied in the range of 2-4 N and the commissural forces varied from 0.4 to 0.8 N with a left ventricular pressure of 111 mmHg. In conclusion, the two new force transducers to measure forces in the aortic root have successfully been developed. With these new devices a novel versatile and direct force measurement system has been provided.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 61, 16 August 2017, Pages 58-64
نویسندگان
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