Effects of D-cycloserine augmentation on cognitive behavioral therapy in patients with obsessive-compulsive disorder: A systematic review and meta-analysis

- D-cycloserine combined with multiple cognitive behavioral therapy sessions effectively stabilize the obsessive-compulsive disorder condition.
- The onset times between DCS and CBT were inconsistent.
- DCS might have been effective in the initial stages, whereas CBT dominated in the middle and late stages.
- Dose timing, human equivalent dose and CBT sessions should be strictly controlled during the DCS treatment.
- The number of CBT sessions was negatively correlated with Y-BOCS scores at follow-up with DCS.