کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
504020 864260 2016 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
3D surface-based registration of ultrasound and histology in prostate cancer imaging
ترجمه فارسی عنوان
ثبت سه بعدی بر روی سطح سونوگرافی و بافت شناسی در تصویربرداری سرطان پروستات
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نرم افزارهای علوم کامپیوتر
چکیده انگلیسی


• We developed a 3D, surface-based, elastic registration algorithm for histology and TRUS imaging.
• To maximize clinical applicability, no auxiliary sensors or dedicated tools were used.
• Several registration techniques were tested during different steps of the algorithm.
• The algorithm was validated in vitro in two gelatin phantoms and in vivo in 7 patients.
• The resulting target registration errors were 1.5 ± 0.2 and 2.1 ± 0.5 mm, respectively.

Several transrectal ultrasound (TRUS)-based techniques aiming at accurate localization of prostate cancer are emerging to improve diagnostics or to assist with focal therapy. However, precise validation prior to introduction into clinical practice is required. Histopathology after radical prostatectomy provides an excellent ground truth, but needs accurate registration with imaging. In this work, a 3D, surface-based, elastic registration method was developed to fuse TRUS images with histopathologic results. To maximize the applicability in clinical practice, no auxiliary sensors or dedicated hardware were used for the registration. The mean registration errors, measured in vitro and in vivo, were 1.5 ± 0.2 and 2.1 ± 0.5 mm, respectively.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computerized Medical Imaging and Graphics - Volume 47, January 2016, Pages 29–39
نویسندگان
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