High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS)

This method was then applied to three hundred authentic samples, resulting in the identification of various drugs of abuse and therapeutic drugs. The analyte identity was subsequently confirmed by in-source fragmentation. Thanks to the scan acquisition, this method also enables retrospective re-analysis of the acquired datafile in case a further analyte needs to be screened.