Metal complexes of Schiff base: Preparation, characterization and antibacterial activity

A total of five new metal complex derivatives of 2N-salicylidene-5-(p-nitro phenyl)-1,3,4-thiadiazole, HL with the metal ions Vo(II), Co(II), Rh(III), Pd(II) and Au(III) have been successfully prepared in alcoholic medium. The complexes obtained are characterized quantitatively and qualitatively by using micro elemental analysis, FTIR spectroscopy, UV-Vis spectroscopy, mass spectroscopy, 1H & 13C NMR, magnetic susceptibility and conductivity measurements. From the spectral study, all the complexes obtained as monomeric structure and the metals center moieties are four-coordinated with square planar geometry except VO(II) and Co complexes which existed as a square pyramidal and tetrahedral geometry respectively. The preliminary in vitro antibacterial screening activity revealed that complexes 1-5 showed moderate activity against tested bacterial strains and slightly higher compared to the ligand, HL.