Effective preparation of 5,5'-(arylmethylene)bis(4-hydroxythiazole-2(3H)-one) in an aqueous fluoroalcohol solvent system under ultrasound irradiation at room temperature

A synthesis of 5,5'-(arylmethylene)bis(4-hydroxythiazole-2(3H)-one) using trifluoroethanol (TFE) as an efficient and recyclable medium in promoting one-pot, pseudo five component reaction is described.