کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5144764 1496869 2017 34 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fabrication of redox and pH dual-responsive magnetic graphene oxide microcapsules via sonochemical method
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Fabrication of redox and pH dual-responsive magnetic graphene oxide microcapsules via sonochemical method
چکیده انگلیسی
In this study, the biocompatible redox and pH dual-responsive magnetic graphene oxide microcapsules (MGOMCs) were prepared by a simple sonochemical method. The disulfide bonds cross-linked the wall of MGOMCs were formed from the hydrosulfuryl on the surface of thiolated graphene oxide, which was synthesized by functionalizing graphene oxide with cysteine, showed an excellent redox-responsive property to control drugs release. Moreover, oleic acid modified Fe3O4 nanoparticles were encapsulated into the microcapsules successfully with the hydrophobic drugs dispersed in the hydroxy silicone oil. The MGOMCs possess distinguished magnetic property and pH-responsive ability. Besides, the microcapsules could be engulfed by Hela cells successfully due to the appropriate size and flexible shell. The MGOMCs could be a good carrier for hydrophobic drugs, especially the anticancer drugs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasonics Sonochemistry - Volume 36, May 2017, Pages 437-445
نویسندگان
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