Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase

Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 128, 10 March 2017, Pages 88-97

Meng Wang, Jiajia Yang, Mengmeng Yuan, Liangmin Xue, Hao Li, Chao Tian, Xiaowei Wang, Junyi Liu, Zhili Zhang,