Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC)

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC)

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 133, 16 June 2017, Pages 329-339

Zhendong Song, Shanshan Huang, Haiqing Yu, Yu Jiang, Changyuan Wang, Qiang Meng, Xiaohong Shu, Hunjun Sun, Kexin Liu, Yanxia Li, Xiaodong Ma,