Amplification yield enhancement of short DNA templates using bulk and surface-attached amine-functionalized single-wall carbon nanotubes

- Amine-functionalized single-wall carbon nanotube dispersion improved the amplification yield of the random sequenced short DNA template (96 bp).
- Amplification yield enhancement was found to be surface charge, dispersion state and DNA template length-dependent.
- Magnetic bead-based nanotubes maintained the amplification enhancement while allowing robust elimination from the reactions.
- Mechanism studies showed a physical interaction between the nanotubes and DNA templates/primers.