Vascular cell responses to ECM produced by smooth muscle cells on TiO2 nanotubes

- TiO2 nanotubes with the tube diameter of 30 nm via anodic oxidation was prepared.
- SMCs on TiO2 nanotubes presented enhanced extracellular matrix secreting.
- ECM prepared via decellularization retained the components: Fn, Ln and collagen.
- ECM-covered TiO2 nanotubes significantly improved the proliferation of ECs.