Folic acid-conjugated Fe3O4 magnetic nanoparticles for hyperthermia and MRI in vitro and in vivo

- The folic acid-conjugated Fe3O4 nanoparticles were synthesized by amidation method.
- The conjugation of folic acid was verified qualitatively by UV-vis spectrum.
- We confirmed the exothermic effect of the nanoparticles in alternating magnetic field.
- The nanoparticles showed targeting effect to KB cells with FA receptors over-expression.