Developing of a novel antibacterial agent by functionalization of graphene oxide with guanidine polymer with enhanced antibacterial activity

- A novel antibacterial material, polyethylene glycol (PEG) and polyhexamethylene guanidine hydrochloride (PHGC) dual-polymer-functionalized graphene oxide (GO) (GO-PEG-PHGC), was synthesized.
- GO-PEG-PHGC had excellent antibacterial activity against E. coli and S. aureus.
- GO-PEG-PHGC shows enhanced antibacterial activity when compared to GO, GO-PEG or GO-PHGC alone, which was described to be related to a better dispersion of GO-PEG-PHGC in the presence of PEG.