Enhancement of antibacterial properties of polyurethanes by chitosan and heparin immobilization

- Polyurethane elastomer was synthesized in medical purity.
- Chitosan (CH) and heparin (Hep) were immobilized on polyurethane films.
- Modification with CH and Hep increased hydrophilicity and surface free energy.
- Immobilized films had high antibacterial activity against four bacteria.
- Bacterial adhesion significantly decreased on the modified surfaces.