کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5357009 | 1503612 | 2015 | 28 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Excimer laser texturing of natural composite polymer surfaces for studying cell-to-substrate specific response
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Excimer laser texturing of natural composite polymer surfaces for studying cell-to-substrate specific response Excimer laser texturing of natural composite polymer surfaces for studying cell-to-substrate specific response](/preview/png/5357009.png)
چکیده انگلیسی
Surface modifications of biocompatible materials are among the main factors used for enhancing and promoting specific cellular activities (e.g. spreading, adhesion, migration, and differentiation) for various types of medical applications such as implants, microfluidic devices, or tissue engineering scaffolds. In this work an excimer laser at 193Â nm was used to fabricate chitosan-collagen roughness gradients. The roughness gradients were obtained in one step by applying single laser pulses and sample tilting. Fourier transform infrared spectroscopy measurements, atomic force microscopy (AFM), scanning electron microscopy (SEM), and spectro-ellipsometry (SE) were used for sample characterization. The goal is to determine the optimal morpho-chemical characteristics of these structures for in vitro tailoring of protein adsorption and cell behavior. The response induced by the roughness gradient onto various cell lines (i.e. L 929 fibroblasts, HEP G2 hepatocytes, OLN 93 oligodendrocytes, M63 osteoblasts) and bovine serum albumin (BSA) protein absorption was investigated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Surface Science - Volume 352, 15 October 2015, Pages 82-90
Journal: Applied Surface Science - Volume 352, 15 October 2015, Pages 82-90
نویسندگان
V. Dinca, P. Alloncle, P. Delaporte, V. Ion, L. Rusen, M. Filipescu, C. Mustaciosu, C. Luculescu, M. Dinescu,