Nanolabel for TNF-α determination

► The nano structured TNF-α has been synthesized applying ANADOLUCA method. ► The bis(2-2′-bipyridyl)bis(MATyr)-ruthenium(II) photosensitive chelate has been synthesized. ► Reflectometric Interference Spectroscopy (RIfS) based sensors have been prepared for selectively recognition and binding of TNF-α.