کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5361706 | 1388276 | 2012 | 8 صفحه PDF | دانلود رایگان |
Polypropylene (PP) fibers can be manufactured to form nets which can find application as prosthesis in hernioplasty.One of the most important problem to deal with when nets are applied in vivo consists in the reproduction of bacteria within the net fibers intersections. This occurs right after the application of the prosthesis, and causes infections, thus it is fundamental to remove bacteria in the very early stage of the nets application.This paper deals with the physico-chemical characterization of such nets, pre-treated by atmospheric pressure plasma dielectric barrier discharge apparatus (APP-DBD) and functionalized with an antibiotic drug such as chitosan.The physico-chemical characterization of sterilized nets, before and after the functionalization with chitosan, was carried out by means of scanning electron microscopy (SEM) coupled with EDS spectroscopy, FTIR spectroscopy, drop shape analysis (DSA), X-ray diffraction and thermal analyses (TGA and DSC).The aim of the work is to individuate a good strategy to characterize this kind of materials, to understand the effects of polypropylene pre-treatment on functionalization efficiency, to follow the materials ageing in order to study the effects of the surface treatment for in vivo applications.
⺠Polypropylene mesh was plasma activated and covered by a chitosan layer to induce antibacterial properties. ⺠A single crystalline isotactic phase for polypropylene fibers (α phase) was observed by XRD and DSC. ⺠Infrared spectroscopy showed the PP fibers surface oxidation after plasma treatment and the effective presence of chitosan. ⺠Chitosan was released in the first few days of soaking, i.e. during the period in which infections usually occur after prosthesis implant.
Journal: Applied Surface Science - Volume 258, Issue 20, 1 August 2012, Pages 7889-7896