Functionalized SBA-15 materials for bilirubin adsorption

To investigate the driving force for bilirubin adsorption on mesoporous materials, a comparative study was carried out between pure siliceous SBA-15 and three functionalized SBA-15 mesoporous materials: CH3-SBA-15 (MS), NH2-SBA-15 (AS), and CH3/NH2-SBA-15 (AMS) that were synthesized by one-pot method. The obtained materials exhibited large surface areas (553-810 m2/g) and pore size (6.6-7.1 nm) demonstrated by XRD and N2-ad/desorption analysis. The SEM images showed that the materials had similar fiberlike morphology. The functionalization extent was calculated according to 29Si MAS NMR spectra and it was close to the designed value (10%). The synthesized mesoporous materials were used as bilirubin adsorbents and showed higher bilirubin adsorption capacities than the commercial active carbon. The adsorption capacities of amine functionalized samples AMS and AS were larger than those of pure siliceous SBA-15 and MS, indicating that electrostatic interaction was the dominant driving force for bilirubin adsorption on mesoporous materials. Increasing the ionic strength of bilirubin solution by adding NaCl would decrease the bilirubin adsorption capacity of mesoporous material, which further demonstrated that the electrostatic interaction was the dominant driving force for bilirubin adsorption. In addition, the hydrophobic interaction provided by methyl groups could promote the bilirubin adsorption.

Research highlights► NH2, CH3-functionalized SBA-15 mesoporous material as bilirubin adsorbent. ► The driving force investigation for bilirubin adsorption on mesoporous materials. ► The electrostatic force dominantly drives bilirubin adsorption. ► The hydrophobic interaction promotes bilirubin adsorption. ► Higher bilirubin adsorption capacity on this bifunctionalized material.