کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5373386 | 1504217 | 2015 | 7 صفحه PDF | دانلود رایگان |
- A formal SFG data analysis approach on bent α-helical structures was proposed.
- The twist angle of α-helical structures was shown to be important in the analysis.
- The interaction between melittin and DPPG was examined by this proposed approach.
- The transient pore model was validated by the data analysis proposed in this study.
Sum Frequency Generation (SFG) has been shown to be a powerful and versatile technique in studies of proteins/peptides at surfaces and interfaces. Recently SFG was successfully applied in studies of interfacial macro-molecules with increasing size and complexity. In this report we continued to employ bond additivity model and group theory to demonstrate the importance of both the inter-helical tilt angle and the lengths of the helical segments assembling the structures being studies. Specifically, a newly improved SFG data analysis of multiple α-helical structures on melittin was used to interpret the SFG experimental observation and also verified the findings with the recent insights brought by other spectroscopic techniques.
Journal: Chemical Physics - Volume 447, 2 February 2015, Pages 15-21