Probing of different conformations of piperazine using Raman spectroscopy

- Most stable conformation of piperazine molecule is equatorial-equatorial chair form.
- Equatorial-equatorial chair form is predominant in pure solid.
- Strongly dipolar equatorial-axial form is most stabilized in aqueous solution.
- Equatorial-axial form vertically binds to Ag/Ag+ through axial N-atom.