Kinetics and thermochemistry of hydrolysis mechanism of a novel anticancer agent trans-[PtCl2(dimethylamine)(isopropylamine)]: A DFT study

- Hydrolysis mechanism of a novel transplain anticancer agent for anticancer activity.
- First hydrolysis step is faster compared to the second step hydrolysis step.
- The structure of transition state structure implies a concerted SN2 mechanism.