Coarse grained simulation reveals antifreeze properties of hyperactive antifreeze protein from Antarctic bacterium Colwellia sp.

- Coarse grained simulation to was used to study the mechanism of Colwellia antifreeze protein (ColAFP).
- Distribution and conformation of ice crystal network surrounding ColAFP as well as phase space and located active conformation of water surrounding ColAFP during the freezing process was identified.