A study of the hydration of lysozyme in neat organic solvents using isothermal calorimetry: Effect of water solvation

- We studied the hydration of lysozyme in neat organic solvents using calorimetry.
- Hydration level of lysozyme was varied from 0 to 0.3 g water/g enzyme.
- The dehydration enthalpies of lysozyme in neat organic liquids were calculated.
- The dehydration enthalpies in organic liquids may be endothermic or exothermic.
- The dehydration enthalpies depend linearly on the water solvation enthalpy.