Vibrational spectra and conformational analysis of desflurane. A cryosolution and ab initio study

- IR spectrum of desflurane in liquid Kr is obtained and analyzed at T ∼ 120-160 K.
- Low frequency vibrations are identified by Raman spectroscopy of pure liquid.
- The temperature changes of IR intensities are of conformational origin.
- Only two most stable conformers contribute to the measured and calculated spectra.