Effects of hydrogen bonding on amide-proton chemical shift anisotropy in a proline-containing model peptide

- Phe3 amide-proton exhibits dipole-CSA cross correlated relaxation.
- Diproline segment causes peptide to adopt cis and trans conformation.
- Intramolecular hydrogen bond exists only in cis conformation.
- Amide-proton CSA is higher due to the presence of hydrogen bond.