A simple quantitative model of macromolecular crowding effects on protein folding: Application to the murine prion protein(121-231)

- We apply a simple model of protein folding kinetics to study the effects of macromolecular crowding.
- Quantitative results for the effects of crowding on protein kinetics and stability are presented.
- The effects of crowding on the protein folding rate and stability are contact order-dependent.