Enhanced photoluminescence of water-soluble Mn-doped ZnS quantum dots by thiol ligand exchange

► We reported the enhanced photoluminescence of Mn:ZnS d-dots by thiol ligand exchange. ► The mechanism for the enhanced PL of thiol-coated Mn:ZnS d-dots has been discussed. ► The quantum yield of the as-synthesized water-soluble dots can reach as high as 50%. ► The efficient and water soluble d-dots are suitable for biomedical applications.