The molecular dynamics and melting transition of the confined ibuprofen in titania nanotube studied by NMR

The bulk ibuprofen melts at 351 K activating rapid molecular reorientation and rapid rotation of isobutyl-group while the confined ibuprofen inside the titania nanotube completely becomes 'liquid-like' at 339 K activating also rapid rotation of isobutyl-group but restricted molecular reorientation. Confinement negligibly affects rotation for all methyl-groups and only slightly accelerates aromatic-ring flipping.