P.E.HSQMBC: Simultaneous measurement of proton-proton and proton-carbon coupling constants

► Reliable measurement of proton-proton and proton-carbon coupling constants from a single 2D cross-peak. ► Simultaneous incorporation of E.COSY and IPAP spin-state selective coupling patterns. ► Long-range proton-carbon coupling constants directly measured from relative cross-peak displacement of α/β multiplets. ► Determination of the relative sign of J(HH).