A large volume double channel 1H-X RF probe for hyperpolarized magnetic resonance at 0.0475Â T

► 340 mL 1H-X probe is developed for NMR of hyperpolarized compounds at 0.0475 T. ► 1H/13C and 1H/15N configurations and 20% PHIP hyperpolarization are demonstrated. ► The probe permits 62 μs excitation 13C pulses at 5.3 W suitable for portable operation. ► 13C sensitivity is compared with a commercial RF probe operating at 4.7 T. ► Low field hyperpolarized MR can be as sensitive as high field detection.