Transfer of hyperpolarization from long T1 storage nuclei to short T1 neighbors using FLOPSY-8

► FLOPSY-8 can transfer hyperpolarized magnetization across a minimum of three bonds. ► Transfer of hyperpolarization depends on the number of FLOPSY-8 cycles. ► Measuring anaplerosis in living systems using FLOPSY-8 and uniform labeling should be possible.